William Blake, the British Romantic poet and artist, is a significant inter-text for Thomas Harris's Hannibal Lecter tetralogy, yet this has been under-researched. In the near future, I will explore all the allusions to Blake in the Hannibal Lecter novels and their film and TV adaptations and demonstrate how the franchise repurposes Blake's idea of good and evil on this website. The Hannibal Lecter series is considered a franchise because it encompasses a wide range of media adaptations based on the novels by Thomas Harris. The combination of novels, films, and TV series, along with the enduring popularity of "Hannibal the Cannibal," contributes to the Hannibal Lecter series being regarded as a franchise. There are many allusions to Blake in Harris's tetralogy. For instance, Francis Dolarhyde, the serial murderer in Red Dragon, has an obsession with Blake's painting The Great Red Dragon and the Woman Clothed in Sun and imagines himself "becoming" the "Red Dragon". In Hannibal, Mason Verger, the sadistic pedophile, owns a copy of Blake's painting The Ancient of Days, which implies Verger's Urizenic qualities.